Evaluation of a Screening Procedure for Basic and Neutral Drugs: N-Butyl Chloride Extraction and Megabore Capillary Gas Chromatography

M.E. Sharp

Canadian Society of Forensic Science Journal · 1986 · 17 citations · 10 references

Concepts

Abstract

A procedure for the comprehensive screening of blood for basic and neutral drugs is described and evaluated. A rapid n-butyl chloride extraction method is used. Extraction recoveries are determined using megabore capillary and packed column gas chromatography with nitrogen-specific detection. Recoveries and retention times are recorded in tabular form. Detection limits are below 200 nanograms of drug per millilitre of blood.

References

10