Increase in Bactericidal Activity as a Result of Injection of Zymosan

Abstract

Summary1. Bactericidal activity against Escherkhia coli B was increased in rabbits and guinea pigs as a result of injections of zymosan mixed with egg-white and incorporated in Freund adjuvants. 2. These rabbits and guinea pigs responded to intracutaneous injection of zymosan with the Arthus phenomenon. 3. Zymosan absorbed the bactericidal activity without affecting the hemolytic activity of the sera. 4. The possible anti-genicity of zymosan is discussed.