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Agelasine G, a New Antileukemic Alkaloid from the Okinawan Marine Sponge Agelas sp.
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1992
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BiologyMarine BiotechnologyBiochemistryNatural SciencesAgelasine GMedicineSecondary MetaboliteBromopyrrole AlkaloidChemical BiologyPharmacologyNew Antileukemic AlkaloidDrug DiscoveryNatural Product Synthesis
A new antileukemic alkaloid, agelasine G (1a), has been isolated from the Okinawan marine sponge Agelas sp. and its structure elucidated to be a bromopyrrole alkaloid containing 9-methyladenine and diterpene moieties on the basis of the spectroscopic data.