Effects of Ethanol on Glucose Utilization in Rat Brain

Abstract

Signs of impairment of utiliztion of glucose in rat brains at 2 1/2 hr after administration of ethanol included increased glucose ratios for cerebrum/blood and hind-brain/blood in fed and fasted rats, decreased concentrations of lactate in cerebrum and hindbrain in fed rats, higher percentages of brain 14C in glucose at 15 min after injection of glucose-U-14C, and decreases in blood glucose equivalents in the combined glucose metabolites in cerebrum and hindbrain of fed and fasted rats.