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Ketone Formation via Mild Nickel-Catalyzed Reductive Coupling of Alkyl Halides with Aryl Acid Chlorides
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Citations
55
References
2012
Year
Chemical EngineeringCross-coupling ReactionEngineeringAlkyl HalidesMild ConditionsOrganic ChemistryUnactivated Alkyl IodidesKetone FormationCatalysisOrganometallic CatalysisChemistryAryl Acid ChloridesCatalytic Synthesis
The present work highlights unprecedented Ni-catalyzed reductive coupling of unactivated alkyl iodides with aryl acid chlorides to efficiently generate alkyl aryl ketones under mild conditions.
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