Concepedia

Ketone Formation via Mild Nickel-Catalyzed Reductive Coupling of Alkyl Halides with Aryl Acid Chlorides

Fan Wu, Wenbin Lu, Qun Qian, Qinghua Ren, Hegui Gong

Organic Letters · 2012 · 145 citations · 55 references

DOI

Concepts

Abstract

The present work highlights unprecedented Ni-catalyzed reductive coupling of unactivated alkyl iodides with aryl acid chlorides to efficiently generate alkyl aryl ketones under mild conditions.

References

55

The Promise and Challenge of Iron-Catalyzed Cross Coupling

Benjamin D. Sherry, Alois Fürstner · Accounts of Chemical Research · 2008 · 1.2K citations

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Catalysts for Cross‐Coupling Reactions with Non‐activated Alkyl Halides

Anja C. Frisch, Matthias Beller · Angewandte Chemie International Edition · 2005 · 915 citations

, , +15

Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective

Xile Hu · Chemical Science · 2011 · 599 citations · Full text

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Ligand Redox Effects in the Synthesis, Electronic Structure, and Reactivity of an Alkyl−Alkyl Cross-Coupling Catalyst

Gavin D. Jones, Jason Martin, Chris McFarland et al. · Journal of the American Chemical Society · 2006 · 486 citations

, , +16

Oxidative Carbonylation Reactions: Organometallic Compounds (RM) or Hydrocarbons (RH) as Nucleophiles

Qiang Liu, Hua Zhang, Aiwen Lei · Angewandte Chemie International Edition · 2011 · 482 citations

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