Antibacterial Activities of <i>Azadirachta</i> <i>Indica</i> against Some Bacterial Pathogens

Abstract

The antibacterial effect of <i>Azadirachta indica</i> against <i>Pseudomonas</i> <i>aeruginosa</i>, <i>Klebsiella</i> <i>ozanae</i>, <i>Staph</i><i>y</i><i>lococcus</i> <i>aureus</i> and <i>Escherichia</i> <i>coli</i> was determined using the agar cup plate technique. The phytochemical components of <i>A. indica</i> showed the presence of saponin and phlobatanin and the absence of alkaloids, tannins, phenolics, glycosides, flavonoids and triterpenes. The result showed that the test organisms were susceptible to 500mg/ml, 50mg/ml and 5mg/ml of the plant extract. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. The result showed that the MIC and MBC were 5mg and 50mg respectively for <i>Pseudomonas aeruginosa, Kl</i>. <i>ozanae</i>, <i>Staphylococcus</i> <i>aureus</i> and <i>Escherichia</i> <i>coli</i>. The result of the study suggests that extracts of <i>A. indica</i> could be suitable for the treatment of various infections caused by <i>P. aeruginosa, K. ozanae, S. aureus </i>and<i> E. coli.</i>