Concepedia

The effect of losartan and captopril on glomerular basement membrane anionic charge in a diabetic rat model

Di̇lek Gogas Yavuz, Önder Ersöz, Belgin Kuçükkaya, Yasemin Budak, Gülsün Ekicioǧlu, Kaya Emerk, Sema Akalın

Journal of Hypertension · 1999 · 14 citations · 38 references

DOI

Abstract

Losartan and captopril have comparable effects on reducing albuminuria in a diabetic rat model. While captopril preserves basement membrane anionic charges, losartan has no effect. The anti-proteinuric effects of these drugs seem to have different mechanisms.

References

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