Non-Susceptibility of Mammals to the Entomopathogenic Bacterium Xenorhabdus nematophilus

Abstract

Guinea pigs, mice, and rats were exposed to Xenorhabdus nematophilus, the entomopathogenic bacterial symbiont of Neoaplectana bibionis, by oral, intradermal, subcutaneous, and intraperitoneal routes, and by inhalation and skin contact. Rabbits were exposed by conjunctival inoculation. There was no evidence of infectivity, pathogenicity, or toxicity in any of the test animals.