Inheritance of Resistance to Permethrin in Culex pipiens quinquefasciatus1

Abstract

The mode of inheritance of resistance to permethrin was studied in 2 strains of the southern house mosquito selected with the d-trans and d-cis isomers of this pyrethroid. Resistance was found to be co dominant (D = −0.014 to 0.14) in the d-trans-selected strain, and partially recessive (D = −0.15 to −0.35) in the d-cis-selected strain. The similarity of dominance values (D) in each pair of reciprocal crosses indicates a lack of sex linkage. Dose response lines for the backcross progeny (F1 ♂×S♀) were significantly different from those which might be expected on the basis of single gene inheritance, leading to the conclusion that permethrin resistance in this mosquito is of polyfactorial origin.