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The Hypolipemic Properties of 2-Acetoamidoethyl (p-chlorophenyl) (m-trifluoromethylphenoxy) acetate in the Rat
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1971
Year
OxysterolPharmacological StudyBiochemistryHypolipemic PropertiesMedicinePhysiologyPharmacological AgentOrganic ChemistryToxicologyPharmacotherapyFree-fatty AcidsPlasma CholesterolDose-response RelationshipCarbonyl MetabolismPharmacologyOxidative Stress
2-Acetoamidoethyl (p-chlorophenyl) (m-trifluoromethylphenoxy) acetate (halofenate) has been established as a potent hypolipemic agent in the rat, significantly lowering, in a dose-response relationship, plasma cholesterol, triglycerides, phospholipids, and free-fatty acids.