Rank Annihilation Factor Analysis of Unresolved LC Peaks

Abstract

Rank annihilation factor analysis (RAFA) of ultraviolet absorbances of unresolved liquid chromatographic fractions is developed and used to individually quantify components of mixtures. A liquid chromatograph, specially designed for RAFA, is described. The method is applied to mixtures containing ethylbenzene, o-xylene and p-xylene.