Alpha-Fetoprotein: Diagnostic and Prognostic Use in Patients with Hepatomas

David T. Purtilo, John H. Kersey, Helen M. Hallgren, Karl R. Fox, Edmond J. Yunis

American Journal of Clinical Pathology · 1973 · 17 citations · 0 references

Concepts

Abstract

The use of alpha-fetoprotein for the detection of hepatocellular carcinomas in two adult patients and a newborn infant is presented. The use of alpha-fetoprotein for monitoring the responses of the hepatomas to surgical resection, irradiation, and chemotherapy is described. Alpha-fetoprotein is illustrated in a hepatocellular carcinoma by indirect immunofluorescence.