Short communications. Subunit A from cholera toxin is an activator of adenylate cyclase in pigeon erythrocytes

Abstract

Intact cholera toxin and its purified subunit A both activate the adenylate cyclase of pigeon erythrocyte membranes, but subunit B does not. The activation by subunit A is unaffected by treatments that inhibit whole toxin by interfering with the binding of subunit B to cell membranes.