Publication | Open Access
Studies on Cyclophosphamide Metabolites and Their Related Compounds. I
40
Citations
0
References
1972
Year
Crystalline MetabolitesHeterocyclicBiochemistryMedicinePhysiologyRabbit UrineSecondary MetaboliteMetabolomicsMetabolismPharmacologyCyclophosphamide MetabolitesPharmaceutical ChemistryDrug Discovery
Two crystalline metabolites (2, 3) of cyclophosphamide (1) were isolated from rabbit urine. The structures of 2 and 3 were determined from their physicochemical data, and confirmed by synthesis. The positions of 2 and 3 in the metabolic pathway of 1 in living animals were discussed briefly.