Metabolic Products of Cholesterol in Bile and Feces of Rat. Steroids and Bile Acids

Abstract

Summary1. After administration of cholesterol-4-C14 to rats the main excretory products in the bile are cholic and chenode-soxycholic acid present as taurine conjugates. 2. The labelled material present in feces has been fractionated. It has been found that most of the conjugate has been split. No unchanged cholic acid seems to be left in the feces. A series of different labelled products have been separated some at least of which contain ketonic groups.