Journal of Applied Probability · 1976 · 176 citations · 7 references
Life SciencesEvolutionary BiologyGeneticsEvolutionary GeneticsPopulation BiologyPopulation GeneticsAllele Frequency DynamicsDemographic StochasticityDiffusion ProcessesGenetic DriftPopulation StructureEquilibrium Allele FrequenciesStationary States
An expression is found for the stationary density of the allele frequencies, in the infinitely-many alleles model. It is assumed that all alleles are neutral, that there is a constant mutation rate, and that the population is sufficiently large for the diffusion model to apply. Bounds on some moments are calculated from the density, and some applications are made to the problem of which allele is oldest in a population. A postulate made by Ewens (1972), concerning the distribution of allele numbers in a finite random sample from the neutral diffusion population, is shown to be correct.
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Handbook of Mathematical Functions
Donald A. McQuarrie · American Journal of Physics · 1966 · 40.9K citations
The sampling theory of selectively neutral alleles
Warren J. Ewens · Theoretical Population Biology · 1972 · 2.2K citations
Is the most frequent allele the oldest?
G. A. Watterson, H. A. Guess · Theoretical Population Biology · 1977 · 274 citations