Regional Lung Functional Impairment in Acute Airway Obstruction and Pulmonary Embolic Dog Models Assessed With Gadolinium-Based Aerosol Ventilation and Perfusion Magnetic Resonance Imaging

Abstract

Gd-based aerosol can provide efficient lung enhancement in spontaneously and adequately breathing animals, using a relatively noninvasive aerosol delivery system. The combined use of Gd-based perfusion MR imaging may be acceptable for defining regionally impaired function associated with acute AO and PE.