Physiological Control of Nitric Oxide in Neuronal <i>BACE1</i> Translation by Heme-Regulated eIF2α Kinase HRI Induces Synaptogenesis - Concepedia

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Physiological Control of Nitric Oxide in Neuronal <i>BACE1</i> Translation by Heme-Regulated eIF2α Kinase HRI Induces Synaptogenesis

DOI Full Paper Access

33

Citations

31

References

2015

Year

Gerard ILL‐Raga, Marta Tajes, Arnau Busquets-García, Eva Ramos‐Fernández, Lina Moitoso de Vargas, Mònica Bosch-Morató, Biuse Guivernau, Victòria Valls-Comamala, Abel Eraso‐Pichot, Francesc X. Guix,

Antioxidants and Redox Signaling

Abstract

We conclude that BACE1 translation is controlled by NO through HRI in glutamatergic hippocampal synapses, where it plays physiological functions, allowing the spine growth and memory consolidation.

References

	Year	Citations

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