Challenges in Recruitment to a Randomized Controlled Study of Cardiovascular Disease Reduction in Sleep Apnea: An Analysis of Alternative Strategies

Abstract

Large resources may be needed to meet the recruitment goals of sleep apnea intervention trials. Recruitment source and mode influence efficiencies. For a trial comparing active versus sham continuous positive airway pressure in patients with CV risk factors, recruiting from cardiology was more efficient than from sleep clinics. MBR was three times less costly than F2F recruitment.