Clinical Nuclear Medicine · 2012 · 16 citations · 0 references
MedicineNeurologyRadiologyHybrid ImagingNeuro-oncologyNeuroradiologyBrain ImagingBrain TumorsCentral Nervous System TumorsMagnetic Resonance ImagingParkinson DiseaseParkinsonian DisordersBrain Tumor PathologyDopamine Receptor ImagingDopamine TransportersNeuroimaging In Parkinson's DiseaseNigrostriatal Dopamine SystemParkinson Disease ImagingParkinson Disease PathologyParkinsonism Imaging
A 58-year-old woman presented with shuffling gait with small steps for 3 months. Tc-TRODAT-1 dopamine transporter SPECT/CT was prescribed to detect the function of the nigrostriatal system. It disclosed absence of uptake in the left putamen and diffusely decreased uptake in the right striatum. An unexpected mass with uneven uptake over the right frontal lobe was also noted. MRI demonstrated a large dura-related tumor, which was later proved as a meningioma after surgical intervention. Meningioma is the most common cause of tumor-induced parkinsonism. This case points to the significance of functional and structural fused neuroimaging in the evaluation of parkinsonism.