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In vivo Inhibition of Liver and Brain Monoamine Oxidase by 1-Isonicotinyl-2-Isopropyl Hydrazine.

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1952

Year

Abstract

SummaryAfter the subcutaneous injection of l-isonicotinyl-2-isopropyl hydrazine (IIH) into rats and guinea pigs, the monoamine oxidase activity of liver homogenates, liver mitochondria, and brain mitochondria is almost completely inhibited. The probable significance of such an inhibition is indicated.