Dopamine-Mediated Continuous Assembly of Biodegradable Capsules

Abstract

PGA-dopamine conjugates (PGAPDA) were synthesized and assembled onto silica particles to yield biodegradable capsules with tunable degradation properties. Increasing the dopamine content results in thicker films with a concomitant reduction in the degradation kinetics. These tailored capsules are expected to find application in diverse areas, including drug and gene delivery.