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Specific Chemotherapy of Experimental Staphylococcus Infections with Thiazol Derivatives of Sulfanilamide
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1939
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Bioorganic ChemistryMouse Virulent StrainAntibiotic AdjuvantSpecific ChemotherapyStaphylococcus AureusAntimicrobial ChemotherapyOther OrgansDrug ResistanceToxicologyInfection ControlAntimicrobial ResistanceAntibacterial AgentAntimicrobial CompoundThiazol DerivativesPharmacologyExperimental Staphylococcus InfectionsAntimicrobial SusceptibilityAntibioticsMicrobiologyMedicineDrug Discovery
ConclusionsSulfathiazol and sulfamethylthiazol prolong the life of mice infected experimentally with a highly mouse virulent strain of Staphylococcus aureus and prevent the development and allow healing of abscesses in kidneys and other organs in a significant number of animals.