Sample size calculation

TLDR

Marine flora and fauna provide bioactive compounds that have been used historically and are now being studied in advanced clinical trials, with some already marketed as drugs. The article reviews current screening trends and activity analysis of marine metabolites, aiming to expose new models and mechanisms of action to address major public health problems. The study summarizes screening methods for bioactive compounds from marine animals and microorganisms, discusses new approaches, and reviews current trends in metabolite activity analysis.

Abstract

Bioactive compounds from marine flora and fauna have extensive past and present use in the treatment of many diseases and serve as compounds of interest both in their natural form and as templates for synthetic modification. Several molecules isolated from various marine organisms (microorganisms, algae, fungi, invertebrates, and vertebrates) are currently under study at an advanced stage of clinical trials, some of them have already been marketed as drugs. This article gives an overview of current trends in screening and the activity analysis of metabolites from marine resources. Although the marine resources have been somewhat limited to date, selected bioactive from marine flora and fauna have already published. This report summarizes the screening for bioactive compounds of marine animals and marine microorganisms. Finally, new approaches for the screening of metabolites from marine resources are discussed. The goal of this article is to expose the new models and mechanisms of action of marine substances to bring new solutions for tackling some of the major public health problems.