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STRUCTURE AND ENZYMATIC BREAK-DOWN OF PROTEINS
104
Citations
0
References
1950
Year
Protein AssemblyPeptide EngineeringMolecular BiologyPeptide SciencePeptide TherapeuticsPeptide ChemistryAnalytical UltracentrifugationChemical BiologyProtein RefoldingPeptide Chain StructureProtein FoldingProteomicsProtein ChemistryBiochemistryPeptide BondsMolecular ModelingStructural BiologyBiomolecular EngineeringSame EnzymesNatural SciencesPeptide LibraryPeptide TherapeuticPeptide SynthesisMedicine
Since the beginning of quantitative research in the field of protein chemistry much weight has been laid upon investigations attempting to prove that proteins are attacked by the same enzymes that are able to split peptide bonds in the simpler compounds. Numerous more or less reliable demonstrations of this fact have been regarded as valuable evidence that proteins have a peptide chain structure. On various occasions (Linderstrøm-Lang, 1933, 1939a, b) the author has issued warnings against a too optimistic opinion about this line of argumentation, the main points being: