<i>C</i>-Acylation of Cyclopropanols: Preparation of Functionalized 1,4-Diketones

Abstract

A convenient method for preparing attractively functionalized 1,4-diketones has been devised by palladium-catalyzed cross-coupling of cyclopropanols and acyl chlorides. The utility of this method has been demonstrated in an enantioselective synthesis of (+)-myrmicarin 217.