Effects of Hyperbaric Oxygen and Hyperbaric Air on the Survival of Island Skin Flaps

Cissy M. Tan, Michael J. Im, Roy A.M. Myers, John E. Hoopes, John E. Hoopes

Plastic & Reconstructive Surgery · 1984 · 46 citations · 0 references

Concepts

Abstract

The effects of hyperbaric air and oxygen on skin survival were studied in acute 8 X 8 cm neurovascular island flaps in rats. Skin flaps treated with hyperbaric 8% oxygen (equivalent to room air at standard pressure) exhibited no improvement in skin survival. Skin flaps treated with hyperbaric air (21% oxygen) and hyperbaric 100% oxygen exhibited significant increases in survival.