Dimethyl Sulfoxide (DMSO) as a Solvent in Acute Toxicity Determinations

H. Rosen, Albert Blumenthal, R. Panasevich, Jeffrey C. McCallum

Experimental Biology and Medicine · 1965 · 34 citations · 0 references

Concepts

Abstract

SummaryDimethyl sulfoxide and water were compared as solvents for determination of LD50 values by the oral route in rats and mice using 10 quaternary ammonium salts as test compounds. Toxicity chan...