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Mechanical Transients and the Origin of Muscular Force
238
Citations
0
References
1973
Year
Muscle FunctionEngineeringContraction MechanismMathematical BiophysicsMotor ControlMechanotransductionAnatomyBiomedical EngineeringContracting Muscle FiberMuscle PhysiologySkeletal MuscleMechanicsBiomechanicsBiophysicsMechanobiologySliding-filament TheoryMechanical TransientsPattern FormationFiber StructurePhysiologyExperimental BiophysicsMedicine
The invitation to contribute to a symposium of this kind gives an opportunity for writing in a more discursive, and a more speculative, way than is accepted in papers for regular scientific journals. An invitation in 1955 to contribute to Progress in Biophysics gave one of us a similar opportunity (A. F. Huxley, 1957) to present some ideas on the details of the contraction mechanism that had arisen through thinking in terms of the sliding-filament theory. Our experimental work since then has consisted largely in following up some of the consequences of those ideas, and it is therefore appropriate to combine a discussion of our present ideas on the origin of force in a contracting muscle fiber with a review of the scheme put forward in 1957.