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Synthesis and pharmacological properties of 8-chloro-10-(2-dimethylaminoethoxy)dibenzo[b,f]thiepin and related compounds. Neurotropic and psychotropic agents. III.
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1978
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Medicinal ChemistryDerivative (Chemistry)Psychotropic AgentsMedicineNatural SciencesPsychotropic MedicationPharmacological PropertiesCompounds 4Pharmacological AgentNeuropharmacologyOrganic ChemistryPharmacotherapyNeuroscienceChemistryRelated CompoundsPharmacologyPharmaceutical ChemistryDrug Discovery
8-Chloro-10-(2-dimethylaminoethoxy) dibenzo [b, f] thiepin (4) and related compounds were prepared by various methods. The results from the pharmacological investigation suggest that many of these compounds will be a kind of neuroleptics and the clinical investigation of the compounds 4 as a neuroleptic is underway.