HTLV-II–Associated Cutaneous T-Cell Lymphoma in a Patient with HIV-1 Infection

Abstract

Patients infected with human immunodeficiency virus type 1 (HIV-1) are susceptible to neoplasms, including Kaposi's sarcoma, non-Hodgkin's lymphoma, and anal and cervical carcinoma.1–5 Some of these neoplasms have been associated with oncogenic infectious agents such as human herpesvirus 8 (HHV-8), Epstein–Barr virus (EBV), human T-cell leukemia–lymphoma virus type I (also known as human T-cell lymphotropic virus type I; HTLV-I), and the human papillomavirus (HPV).1–5 Presumably, the immunosuppression caused by HIV-1 allows for the expansion of virally transformed cells and the development of cancer. HTLV-I and human T-cell lymphotropic virus type II (HTLV-II) are oncogenic retroviruses.6,7 HTLV-I infects . . .