Mild and Selective C(CO)–C(α) Bond Activation of Ketones with Rhodium(III) Porphyrin β-Hydroxyethyl

Abstract

Rhodium(III) porphyrin β-hydroxyethyl, RhIII(ttp)CH2CH2OH (ttp = 5,10,15,20-tetratolylporphyrinato dianion), was found to serve as a precursor of the highly reactive RhIII(ttp)OH for the C(CO)–C(α) bond activation (CCA) of ketones under mild and aerobic conditions of 25–50 °C.