Plasma Volume and Arterial Stiffness in the Cardiac Alterations Associated With Long-Term High Sodium Feeding in Rats

Abstract

High sodium intake was associated with concentric cardiac hypertrophy without change of systolic and diastolic function. Aortic rigidity was not a determinant of cardiac hypertrophy. Beside a likely direct effect of sodium on cardiovascular system the slight increase in arterial pressure and plasma volume play a role.