Inhibition of Respiration of Dysentery Bacilli by Sulfapyridine.

Abstract

It has been found that sulfapyridine in concentrations of 30 mg % inhibits the stimulation of respiration due to nicotin-amide. This inhibition is apparently competitive since the sulfapyridine must be added prior to the addition of the nicotinamide to obtain this effect. While percentage inhibition has varied in different experiments, sufficient experimental data have been obtained so as to leave no doubt as to the validity of the inhibition.