Antibody Production in the Guinea Pig to Homologous Uvea.

Abstract

The immune response of guinea pigs to homologous uvea was studied, using various periods of immunization and the complement fixation test for detection of antibody. Injections over relatively long periods of time with uveal emulsions led to both antibody production and ocular lesions. Demonstrable antibody and ocular lesions were not found on short term immunization. The antigen herein described was both organ and species specific, in contrast to other uveal organ specific antigens previously described which are heterogenetic.