New England Journal of Medicine · 1955 · 56 citations · 6 references
GastroenterologyDigestive TractGastrointestinal Peptide HormoneBioanalysisHematologyClinical ChemistryLaboratory MedicineHealth SciencesGastric Secretory Activity1Transfusion MedicineChemical PathologyEndocrinologyPharmacologyBlood Pepsin AssayBlood DonationUrologyGastric SecretionConventional StudyPhysiologyMedicineNephrologyBlood Transfusion
CONVENTIONAL study of gastric secretion is limited by several factors, including the effect of the tube in the stomach. Such an unpleasant procedure may stimulate or may inhibit gastric secretion; indeed, it may be so distasteful as to preclude passage of the tube. Therefore, re-emphasis on the fact that peptic activity in the urine reflects gastric secretory activity1 stimulated much research into this more physiologic approach. Still, even urine collections were uncertain, and it was suggested that changes in water and electrolyte balance and in renal clearance might affect uropepsin excretion.Mirsky et al.,2 in 1952, described a method of . . .
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