Carbon Monoxide Protects Against Hemorrhagic Shock and Resuscitation–Induced Microcirculatory Injury and Tissue Injury

Abstract

Hemorrhagic shock/resuscitation is associated with endothelial injury. Heme oxygenase enzymes and CO are involved in part in diminishing this injury and may prove useful as a therapeutic adjunct that can be harnessed to protect against endothelial activation and damage.