High-density lipoprotein concentrations relate to the clinical course of HIV viral load in patients undergoing antiretroviral therapy

Abstract

High levels of HDL-cholesterol are associated with a better viral response in treated HIV patients. This association could be related to the sequence similarity and structure homology between apolipoprotein A1 and p17 Gag-HIV protein, which raises the intriguing clinical possibility that inducing an increase in HDL could assist HIV therapy.