Different clinical presentations of Naxos disease and Carvajal syndrome: Case series from a single tertiary center and review of the literature

Abstract

For cases with woolly hair and palmoplantar keratoderma, the physician should provide a cardiac assessment, considering Naxos/Carvajal disease associated with cardiomyopathy. When an early diagnosis is made, the life expectancy may be increased by treatment of heart failure and arrhythmias; also, genetic counseling should be performed.