Primary Cutaneous Histoplasmosis

Abstract

THE criteria suggested by several investigators1 , 2 as necessary to establish a diagnosis of primary cutaneous infection with a fungus capable of causing pulmonary mycosis are as follows: history of traumatic inoculation, with subsequent development of a chancriform lesion within three or four weeks at the point of trauma; evidence that the wound was contaminated with the causative fungus; development of lymphangitis and regional lymphadenopathy; no history or clinical or laboratory evidence of previous pulmonary or systemic mycosis; and conversion of the skin test from negative to positive and rising serologic titer (where applicable). This sequence of events, which Wilson3 calls . . .