Effects of Mannoheptulose on Glucose Metabolism of Isolated Tissues

Abstract

The mechanism of the diabetogenic action of mannoheptulose has been investigated by testing its action on glucose metabolism by isolated tissues. Mannoheptulose did not alter the in vitro metabolism of glucose by liver, kidney, diaphragm or epididymal fat pad. The stimulating effects of insulin on glucose metabolism of diaphragm and adipose tissue were not decreased by mannoheptulose.