Hyperuricemia in Primary and Renal Hypertension

Abstract

AN increased incidence of hyperuricemia in patients with primary hypertension has been cited in several reports.1 2 3 The present investigation of the population of the Hypertension-Nephritis Clinic of the Presbyterian Hospital in New York City confirms this observation among patients with either primary or renal hypertension, treated and untreated. The data from a related series of studies suggest that the hyperuricemia in both types of hypertension results from diminished renal excretion of urate. Altered lactic acid metabolism in hypertensive disease may account in part for the altered renal transport of uric acid.4 The results also raise the possibility that elevations of . . .