Entropy Dominated High Performance Liquid Chromatographic Separations of Polynuclear Aromatic Hydrocarbons. Temperature as a Separation Parameter

Abstract

The effect of temperature variations on the thermodynamic distribution behaviour in a silica C18/aqueous acetonitrile chromatographic system of polynuclear aromatic hydrocarbons is discussed. Evaluated enthalpy and calculated entropy change values are presented. The elution sequences of some polynuclear aromatic hydrocarbons are reversed by temperature variations, which ascribed to domination by entropy effects.