Syntheses of ornithine decarboxylase inhibitors: D- and DL-.ALPHA.-hydrazinoornithine.

Abstract

The absolute configuration of optically active α-hydrazinoornithine which was prepared by the reaction of hydrazine with the α-bromo acid derived from L-ornithine was proved to be the D-configuration. In addition, racemic α-hydrazinoornithine was first prepared by two different methods.