Contrast Media Augmented Apoptosis of Cultured Renal Mesangial, Tubular, Epithelial, Endothelial, and Hepatic Cells

Abstract

First, Iomeprol, which has a different physico-chemical properties, proved to be less proapoptotic compared with other contrast compounds. Second, all types of cells similarly respond by apoptosis to contrast media induced injury. However, apoptosis of mesangial cells might generate additional deleterious effects in vivo.