Concepedia

Publication | Open Access

Protective and Antioxidant Effects of PPARα in the Ischemic Retina

DOIFull Paper Access

71

Citations

32

References

2014

Year

Elizabeth Moran, Lexi Ding, Zhongxiao Wang, Rui Cheng, Qian Chen, R L Moore, Yusuke Takahashi, Jian‐xing Ma
Investigative Ophthalmology & Visual Science

Abstract

Peroxisome proliferator-activated receptor-alpha has a potent antiapoptotic effect in the ischemic retina. This protective effect may be mediated in part through downregulation of HIF-1α/Nox 4 and consequently alleviation of oxidative stress.

References

YearCitations

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