Clinical Journal of Pain · 1997 · 60 citations · 12 references
MedicineNeurosurgeryOncologyCancer Pain ManagementPain ManagementPain MedicineAnalgesiaCancer PainOpioid AnalgesicsOpioid TherapyPalliative Pain ManagementPostoperative PainCancer Pain ControlCancer Pain Opioid TherapyCancer-related Pain ControlNeurosurgical Pain ManagementPharmacological Pain ReliefPostoperative Cognitive ImpairmentRefractory Cancer PainRefractory Pain Syndromes
CASE REPORT: Three cases of intractable pain arising from widespread metastatic cancer with poor response to opioids were treated with MRI-guided cingulotomy. RESULTS AND CONCLUSIONS: In most cases, MRI-guided cingulotomy was associated with significant pain relief and reduced opioid use. To provide insight into the role of MRI-guided cingulotomy in oncologic pain refractory to more conservative measures, the relative risks and benefits of cingulotomy are discussed, along with the course of one patient who experienced postoperative cognitive impairment. This report also describes the relevant neurosurgical and pharmacotherapeutic issues associated with management of pain in patients with widespread metastatic disease.
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Multiple Representations of Pain in Human Cerebral Cortex
Jeanne Talbot, Sean Marrett, Alan C. Evans et al. · Science · 1991 · 976 citations
Treatment of psychiatric illness by stereotactic cingulotomy
H. Thomas Ballantine, Anthony Bouckoms, E. Thomas et al. · Biological Psychiatry · 1987 · 328 citations