TNF-Selectokine: a novel prodrug generated for tumor targeting and site-specific activation of tumor necrosis factor

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al. · Nature · 1997 · 3.1K citations

Life Sciences, Cell Biology, Immunology +14

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

Matthias Grell, Eleni Douni, Harald Wajant et al. · Cell · 1995 · 1.3K citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation

David W. Banner, A. D’Arcy, Wolfgang Janes et al. · Cell · 1993 · 1.1K citations

Life Sciences, Biochemistry, Immunology +17

Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers.

Pilar Garin‐Chesa, Lloyd J. Old, Wolfgang J. Rettig · Proceedings of the National Academy of Sciences · 1990 · 738 citations

Veterinary Medicine, Oncology, Pathology +17

Fibroblast Activation Protein, a Dual Specificity Serine Protease Expressed in Reactive Human Tumor Stromal Fibroblasts

John E. Park, Martin Lenter, Rainer N. Zimmermann et al. · Journal of Biological Chemistry · 1999 · 576 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17