Reduced Thymic Size but No Evidence of Impaired Thymic Function in Uninfected Children Born to Human Immunodeficiency Virus-infected Mothers

Abstract

The study demonstrates reduced thymic size in HIV-EU children compared with children born to HIV-negative mothers, but no evidence of impaired thymic function, immune regulation, or antibody vaccination response was detected, suggesting that no qualitative immune deficits persist in HIV-EU children at 15 months of age.