Extraction of a Glucose Uptake Stimulator from Tumors.

Abstract

A material capable of stimulating glucose uptake of rat epididymal fat pads in vitro has been extracted and concentrated by ethanol precipitation, from several neoplastic tissues. Most of the normal tissues assayed did not have significant amounts of the glucose uptake stimulator. In the 2 cases where a stimulator was found in normal tissues, it was present in lower concentrations than in the corresponding tumors.